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Temporal Progression of Aortic Valve Pathogenesis in a Mouse Model of Osteogenesis Imperfecta

Organization of extracellular matrix (ECM) components, including collagens, proteoglycans, and elastin, is essential for maintaining the structure and function of heart valves throughout life. Mutations in ECM genes cause connective tissue disorders, including Osteogenesis Imperfecta (OI), and progr...

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Detalles Bibliográficos
Autores principales: Thatcher, Kaitlyn, Mattern, Carol R., Chaparro, Daniel, Goveas, Veronica, McDermott, Michael R., Fulton, Jessica, Hutcheson, Joshua D., Hoffmann, Brian R., Lincoln, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455328/
https://www.ncbi.nlm.nih.gov/pubmed/37623368
http://dx.doi.org/10.3390/jcdd10080355