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Temporal Progression of Aortic Valve Pathogenesis in a Mouse Model of Osteogenesis Imperfecta
Organization of extracellular matrix (ECM) components, including collagens, proteoglycans, and elastin, is essential for maintaining the structure and function of heart valves throughout life. Mutations in ECM genes cause connective tissue disorders, including Osteogenesis Imperfecta (OI), and progr...
Autores principales: | Thatcher, Kaitlyn, Mattern, Carol R., Chaparro, Daniel, Goveas, Veronica, McDermott, Michael R., Fulton, Jessica, Hutcheson, Joshua D., Hoffmann, Brian R., Lincoln, Joy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455328/ https://www.ncbi.nlm.nih.gov/pubmed/37623368 http://dx.doi.org/10.3390/jcdd10080355 |
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