Histamine H4 Receptor Agonist, 4-Methylhistamine, Aggravates Disease Progression and Promotes Pro-Inflammatory Signaling in B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model

We sought to assess the impact of 4-Methylhistamine (4-MeH), a specific agonist targeting the Histamine H4 Receptor (H4R), on the progression of experimental autoimmune encephalomyelitis (EAE) and gain insight into the underlying mechanism. EAE is a chronic autoimmune, inflammatory, and neurodegener...

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Detalles Bibliográficos
Autores principales: Alsaad, Abdulaziz M. S., Ansari, Mushtaq A., Nadeem, Ahmed, Attia, Sabry M., Bakheet, Saleh A., Alomar, Hatun A., Ahmad, Sheikh F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455358/
https://www.ncbi.nlm.nih.gov/pubmed/37629172
http://dx.doi.org/10.3390/ijms241612991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455358/
https://www.ncbi.nlm.nih.gov/pubmed/37629172
http://dx.doi.org/10.3390/ijms241612991

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