Effect of Siponimod on Brain and Spinal Cord Imaging Markers of Neurodegeneration in the Theiler’s Murine Encephalomyelitis Virus Model of Demyelination

Siponimod (Sp) is a Sphingosine 1-phosphate (S1P) receptor modulator, and it suppresses S1P- mediated autoimmune lymphocyte transport and inflammation. Theiler’s murine encephalomyelitis virus (TMEV) infection mouse model of multiple sclerosis (MS) exhibits inflammation-driven acute and chronic phas...

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Detalles Bibliográficos
Autores principales: Pol, Suyog, Dhanraj, Ravendra, Taher, Anissa, Crever, Mateo, Charbonneau, Taylor, Schweser, Ferdinand, Dwyer, Michael, Zivadinov, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455446/
https://www.ncbi.nlm.nih.gov/pubmed/37629171
http://dx.doi.org/10.3390/ijms241612990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455446/
https://www.ncbi.nlm.nih.gov/pubmed/37629171
http://dx.doi.org/10.3390/ijms241612990

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