Cargando…
Effect of Siponimod on Brain and Spinal Cord Imaging Markers of Neurodegeneration in the Theiler’s Murine Encephalomyelitis Virus Model of Demyelination
Siponimod (Sp) is a Sphingosine 1-phosphate (S1P) receptor modulator, and it suppresses S1P- mediated autoimmune lymphocyte transport and inflammation. Theiler’s murine encephalomyelitis virus (TMEV) infection mouse model of multiple sclerosis (MS) exhibits inflammation-driven acute and chronic phas...
Autores principales: | Pol, Suyog, Dhanraj, Ravendra, Taher, Anissa, Crever, Mateo, Charbonneau, Taylor, Schweser, Ferdinand, Dwyer, Michael, Zivadinov, Robert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455446/ https://www.ncbi.nlm.nih.gov/pubmed/37629171 http://dx.doi.org/10.3390/ijms241612990 |
Ejemplares similares
-
Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis
por: Modica, Claire M., et al.
Publicado: (2017) -
Astrocyte depletion alters extracellular matrix composition in the demyelinating phase of Theiler’s murine encephalomyelitis
por: Allnoch, Lisa, et al.
Publicado: (2022) -
Pathogenesis of Theiler's Murine Encephalomyelitis Virus
por: Yamada, Masahito, et al.
Publicado: (1991) -
Reactive Oxygen Species Are Key Mediators of Demyelination in Canine Distemper Leukoencephalitis but not in Theiler’s Murine Encephalomyelitis
por: Attig, Friederike, et al.
Publicado: (2019) -
Monoclonal antibody to Theiler's murine encephalomyelitis virus defines a determinant on myelin and oligodendrocytes, and augments demyelination in experimental allergic encephalomyelitis
Publicado: (1990)