The Roles of Coenzyme A Binding Pocket Residues in Short and Medium Chain Acyl-CoA Synthetases

Short- and medium-chain acyl-CoA synthetases catalyze similar two-step reactions in which acyl substrate and ATP bind to form an enzyme-bound acyl-adenylate, then CoA binds for formation of the acyl-CoA product. We investigated the roles of active site residues in CoA binding in acetyl-CoA synthetas...

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Detalles Bibliográficos
Autores principales: Meng, Yu, Ingram-Smith, Cheryl, Ahmed, Oly, Smith, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455477/
https://www.ncbi.nlm.nih.gov/pubmed/37629500
http://dx.doi.org/10.3390/life13081643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455477/
https://www.ncbi.nlm.nih.gov/pubmed/37629500
http://dx.doi.org/10.3390/life13081643

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