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Interactions of EGFR/PTEN/mTOR-Pathway Activation and Estrogen Receptor Expression in Cervical Cancer

(1) Objective: Late-line chemotherapy rechallenge in recurrent cervical cancer is associated with modest therapy response but significant side effects. As mTOR pathways modulate cellular growth via estrogen receptor (ER) signaling and combined mTOR and ER inhibition previously demonstrated survival...

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Detalles Bibliográficos
Autores principales: Bartl, Thomas, Grimm, Christoph, Mader, Robert M., Zielinski, Christoph, Prager, Gerald, Unseld, Matthias, Herac-Kornauth, Merima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455725/
https://www.ncbi.nlm.nih.gov/pubmed/37623437
http://dx.doi.org/10.3390/jpm13081186