Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality

Drug-metabolizing enzymes (DMEs) and transporters play a major role in drug efficacy and safety. They are regulated at multiple levels and by multiple factors. Estimating their expression and activity could contribute to predicting drug pharmacokinetics and their regulation by drugs or pathophysiolo...

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Detalles Bibliográficos
Autores principales: Gagliardi, Anna, Bajraktari-Sylejmani, Gzona, Barocelli, Elisabetta, Weiss, Johanna, Rigalli, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455864/
https://www.ncbi.nlm.nih.gov/pubmed/37629602
http://dx.doi.org/10.3390/life13081745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455864/
https://www.ncbi.nlm.nih.gov/pubmed/37629602
http://dx.doi.org/10.3390/life13081745

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