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Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality
Drug-metabolizing enzymes (DMEs) and transporters play a major role in drug efficacy and safety. They are regulated at multiple levels and by multiple factors. Estimating their expression and activity could contribute to predicting drug pharmacokinetics and their regulation by drugs or pathophysiolo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455864/ https://www.ncbi.nlm.nih.gov/pubmed/37629602 http://dx.doi.org/10.3390/life13081745 |