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Proteomic Profiling of Paracoccidioides brasiliensis in Response to Phenacylideneoxindol Derivative: Unveiling Molecular Targets and Pathways

Background: The treatment of paracoccidioidomycosis (PCM) is a challenge, and the discovery of new antifungal compounds is crucial. The phenacylideneoxindoles exhibited promising antifungal activity against Paracoccidioides spp., but their mode of action remains unknown. Methods: Through proteomic a...

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Detalles Bibliográficos
Autores principales: Silva, Lívia do Carmo, Rocha, Olivia Basso, Portis, Igor Godinho, Santos, Thaynara Gonzaga, Freitas e Silva, Kleber Santiago, dos Santos Filho, Raimundo Francisco, Cunha, Silvio, Alonso, Antônio, Soares, Célia Maria de Almeida, Pereira, Maristela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455990/
https://www.ncbi.nlm.nih.gov/pubmed/37623625
http://dx.doi.org/10.3390/jof9080854