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Maternal metabolic status and in-vitro culture conditions during embryonic genome activation deregulate the expression of energy-related genes in the bovine 16-cells embryo

The molecular consequences of the metabolic stress caused by milk production of dairy cows in the early embryo are largely unknown. The objective was to determine the impact of dam metabolic status or in vitro culture during embryonic genome activation (EGA) on the transcriptomic profiles of bovine...

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Detalles Bibliográficos
Autores principales: Rabaglino, Maria B., Forde, Niamh, Besenfelder, Urban, Havlicek, Vitezslav, Blum, Helmut, Graf, Alexander, Wolf, Eckhard, Lonergan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456174/
https://www.ncbi.nlm.nih.gov/pubmed/37624829
http://dx.doi.org/10.1371/journal.pone.0290689