Hypothesis-generating analysis of the impact of non-damaging metabolic acidosis on the transcriptome of different cell types: Integrated stress response (ISR) modulation as general transcriptomic reaction to non-respiratory acidic stress?

Extracellular pH is an important parameter influencing cell function and fate. Microenvironmental acidosis accompanies different pathological situations, including inflammation, hypoxia and ischemia. Research focussed mainly on acidification of the tumour micromilieu and the possible consequences on...

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Detalles Bibliográficos
Autores principales: Dubourg, Virginie, Schulz, Marie-Christin, Terpe, Philipp, Ruhs, Stefanie, Kopf, Michael, Gekle, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456223/
https://www.ncbi.nlm.nih.gov/pubmed/37624790
http://dx.doi.org/10.1371/journal.pone.0290373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456223/
https://www.ncbi.nlm.nih.gov/pubmed/37624790
http://dx.doi.org/10.1371/journal.pone.0290373

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