Metformin Can Attenuate Beta-Cell Hypersecretion—Implications for Treatment of Children with Obesity

In children with obesity, insulin hypersecretion is proposed to precede insulin resistance. We investigated if metformin could be used to attenuate insulin secretion from palmitate-treated isolated islets and its implication for children with obesity. Human islets were exposed to palmitate for 0.5 o...

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Detalles Bibliográficos
Autores principales: Wen, Quan, Stenlid, Rasmus, Chowdhury, Azazul Islam, Ciba, Iris, Aydin, Banu, Cerenius, Sara Y., Manell, Hannes, Forslund, Anders, Bergsten, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456302/
https://www.ncbi.nlm.nih.gov/pubmed/37623862
http://dx.doi.org/10.3390/metabo13080917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456302/
https://www.ncbi.nlm.nih.gov/pubmed/37623862
http://dx.doi.org/10.3390/metabo13080917

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