The Impacts of Slc19a3 Deletion and Intestinal SLC19A3 Insertion on Thiamine Distribution and Brain Metabolism in the Mouse

The Thiamine Transporter 2 (THTR2) encoded by SLC19A3 plays an ill-defined role in the maintenance of tissue thiamine, thiamine monophosphate, and thiamine diphosphate (TDP) levels. To evaluate the impact of THTR2 on tissue thiamine status and metabolism, we expressed the human SLC19A3 transgene in...

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Detalles Bibliográficos
Autores principales: Wen, Anita, Zhu, Ying, Yee, Sook Wah, Park, Brian I., Giacomini, Kathleen M., Greenberg, Andrew S., Newman, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456376/
https://www.ncbi.nlm.nih.gov/pubmed/37623829
http://dx.doi.org/10.3390/metabo13080885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456376/
https://www.ncbi.nlm.nih.gov/pubmed/37623829
http://dx.doi.org/10.3390/metabo13080885

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