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The Urine Metabolome of R6/2 and zQ175DN Huntington’s Disease Mouse Models

Huntington’s disease (HD) is caused by the expansion of a polyglutamine (polyQ)-encoding tract in exon 1 of the huntingtin gene to greater than 35 CAG repeats. It typically has a disease course lasting 15–20 years, and there are currently no disease-modifying therapies available. Thus, there is a ne...

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Detalles Bibliográficos
Autores principales: Speziale, Roberto, Montesano, Camilla, Di Pietro, Giulia, Cicero, Daniel Oscar, Summa, Vincenzo, Monteagudo, Edith, Orsatti, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456449/
https://www.ncbi.nlm.nih.gov/pubmed/37623904
http://dx.doi.org/10.3390/metabo13080961