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Sustained Delivery of the Antiviral Protein Griffithsin and Its Adhesion to a Biological Surface by a Silk Fibroin Scaffold

The protein Griffithsin (Grft) is a lectin that tightly binds to high-mannose glycosylation sites on viral surfaces. This property allows Grft to potently inhibit many viruses, including HIV-1. The major route of HIV infection is through sexual activity, so an important tool for reducing the risk of...

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Detalles Bibliográficos
Autores principales: Guan, Wenyan, Zhang, Ning, Bains, Arjan, Martinez, Airam, LiWang, Patricia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456748/
https://www.ncbi.nlm.nih.gov/pubmed/37629837
http://dx.doi.org/10.3390/ma16165547