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Sustained Delivery of the Antiviral Protein Griffithsin and Its Adhesion to a Biological Surface by a Silk Fibroin Scaffold
The protein Griffithsin (Grft) is a lectin that tightly binds to high-mannose glycosylation sites on viral surfaces. This property allows Grft to potently inhibit many viruses, including HIV-1. The major route of HIV infection is through sexual activity, so an important tool for reducing the risk of...
Autores principales: | Guan, Wenyan, Zhang, Ning, Bains, Arjan, Martinez, Airam, LiWang, Patricia J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456748/ https://www.ncbi.nlm.nih.gov/pubmed/37629837 http://dx.doi.org/10.3390/ma16165547 |
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