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ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy

Mitochondrial permeability transition pore (MPTP) formation contributes to ischemia-reperfusion injury in the heart and several degenerative diseases, including muscular dystrophy (MD). MD is a family of genetic disorders characterized by progressive muscle necrosis and premature death. It has been...

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Detalles Bibliográficos
Autores principales: Bround, Michael J., Havens, Julian R., York, Allen J., Sargent, Michelle A., Karch, Jason, Molkentin, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456852/
https://www.ncbi.nlm.nih.gov/pubmed/37624892
http://dx.doi.org/10.1126/sciadv.adi2767