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Human Skin Drug Metabolism: Relationships between Methyl Salicylate Metabolism and Esterase Activities in IVPT Skin Membranes

The presence of esterase enzymes in human skin and their role in drug metabolism has been reported, but their distribution in the various skin layers and the relative contributions of those layers to metabolism is poorly defined. To gain further insight into esterase distribution, we performed in vi...

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Detalles Bibliográficos
Autores principales: Telaprolu, Krishna C., Grice, Jeffrey E., Mohammed, Yousuf H., Roberts, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456861/
https://www.ncbi.nlm.nih.gov/pubmed/37623877
http://dx.doi.org/10.3390/metabo13080934