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Spf1 and Ste24: quality controllers of transmembrane protein topology in the eukaryotic cell
DNA replication, transcription, and translation in eukaryotic cells occur with decreasing but still high fidelity. In contrast, for the estimated 33% of the human proteome that is inserted as transmembrane (TM) proteins, insertion with a non-functional inverted topology is frequent. Correct topology...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456885/ https://www.ncbi.nlm.nih.gov/pubmed/37635876 http://dx.doi.org/10.3389/fcell.2023.1220441 |