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Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines

Although metabolic alterations are observed in many monogenic and complex genetic disorders, the impact of most mammalian genes on cellular metabolism remains unknown. Understanding the effect of mouse gene dysfunction on metabolism can inform the functions of their human orthologues. We investigate...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Barupal, Dinesh K., Fan, Sili, Gao, Bei, Zhu, Chao, Flenniken, Ann M., McKerlie, Colin, Nutter, Lauryl M. J., Lloyd, Kevin C. Kent, Fiehn, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456929/
https://www.ncbi.nlm.nih.gov/pubmed/37623890
http://dx.doi.org/10.3390/metabo13080947