Cargando…
Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines
Although metabolic alterations are observed in many monogenic and complex genetic disorders, the impact of most mammalian genes on cellular metabolism remains unknown. Understanding the effect of mouse gene dysfunction on metabolism can inform the functions of their human orthologues. We investigate...
Autores principales: | Zhang, Ying, Barupal, Dinesh K., Fan, Sili, Gao, Bei, Zhu, Chao, Flenniken, Ann M., McKerlie, Colin, Nutter, Lauryl M. J., Lloyd, Kevin C. Kent, Fiehn, Oliver |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456929/ https://www.ncbi.nlm.nih.gov/pubmed/37623890 http://dx.doi.org/10.3390/metabo13080947 |
Ejemplares similares
-
A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium
por: Barupal, Dinesh K., et al.
Publicado: (2019) -
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma
por: Mohammed, Yassene, et al.
Publicado: (2021) -
Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function
por: Moore, Bret A., et al.
Publicado: (2019) -
Metabox: A Toolbox for Metabolomic Data Analysis, Interpretation and Integrative Exploration
por: Wanichthanarak, Kwanjeera, et al.
Publicado: (2017) -
IDSL.GOA: Gene Ontology Analysis for Metabolomics
por: Mahajan, Priyanka, et al.
Publicado: (2023)