Triple Therapy with Metformin, Ketogenic Diet, and Metronomic Cyclophosphamide Reduced Tumor Growth in MYCN-Amplified Neuroblastoma Xenografts

Neuroblastoma (NB) is a childhood cancer in which amplification of the MYCN gene is the most acknowledged marker of poor prognosis. MYCN-amplified NB cells rely on both glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) for energy production. Previously, we demonstrated that a ketogenic...

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Detalles Bibliográficos
Autores principales: Catalano, Luca, Aminzadeh-Gohari, Sepideh, Weber, Daniela D., Poupardin, Rodolphe, Stefan, Victoria E., Smiles, William J., Tevini, Julia, Feichtinger, René G., Derdak, Sophia, Bilban, Martin, Bareswill, Stefan, Heimesaat, Markus M., Kofler, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456943/
https://www.ncbi.nlm.nih.gov/pubmed/37623854
http://dx.doi.org/10.3390/metabo13080910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10456943/
https://www.ncbi.nlm.nih.gov/pubmed/37623854
http://dx.doi.org/10.3390/metabo13080910

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