Inhibition of BACE1 attenuates microglia-induced neuroinflammation after intracerebral hemorrhage by suppressing STAT3 activation

Hematoma-induced neuroinflammation is the cause of poor prognosis in intracerebral hemorrhage (ICH); therefore, promoting blood clearance and blocking overactivated inflammation are rational approaches for ICH treatment. β-site amyloid precursor protein (APP) lyase-1 (BACE1) is a key molecule regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Jianfeng, Cao, Yang, Guo, Gengyin, Li, Maogui, Zhang, Tongfu, He, Dong, Chen, Jinyan, Zhang, Keke, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457076/
https://www.ncbi.nlm.nih.gov/pubmed/37552127
http://dx.doi.org/10.18632/aging.204935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457076/
https://www.ncbi.nlm.nih.gov/pubmed/37552127
http://dx.doi.org/10.18632/aging.204935

Ejemplares similares