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Regeneration of the cerebral cortex by direct chemical reprogramming of macrophages into neuronal cells in acute ischemic stroke

Theoretically, direct chemical reprogramming of somatic cells into neurons in the infarct area represents a promising regenerative therapy for ischemic stroke. Previous studies have reported that human fibroblasts and astrocytes transdifferentiate into neuronal cells in the presence of small molecul...

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Detalles Bibliográficos
Autores principales: Ninomiya, Itaru, Koyama, Akihide, Otsu, Yutaka, Onodera, Osamu, Kanazawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457112/
https://www.ncbi.nlm.nih.gov/pubmed/37636590
http://dx.doi.org/10.3389/fncel.2023.1225504