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A C/ebpα isoform specific differentiation program in immortalized myelocytes

The transcription factor CCAAT-enhancer binding factor alpha (C/ebpα) is a master controller of myeloid differentiation that is expressed as long (p42) and short (p30) isoform. Mutations within the CEBPA gene selectively deleting p42 are frequent in human acute myeloid leukemia. Here we investigated...

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Detalles Bibliográficos
Autores principales: Garcia-Cuellar, Maria-Paz, Akan, Selin, Slany, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457184/
https://www.ncbi.nlm.nih.gov/pubmed/37532789
http://dx.doi.org/10.1038/s41375-023-01989-8