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Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice
Increased expression of the voltage-gated potassium channel Kv1.3 in activated microglia, and the subsequent release of pro-inflammatory mediators, are closely associated with the progression of Alzheimer’s disease (AD). Studies have shown that reducing neuroinflammation through the non-selective bl...
Autores principales: | Pan, Yijun, Kagawa, Yoshiteru, Sun, Jiaqi, Lucas, Deanna S. Deveson, Takechi, Ryusuke, Mamo, John C. L., Wai, Dorothy C. C., Norton, Raymond S., Jin, Liang, Nicolazzo, Joseph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457257/ https://www.ncbi.nlm.nih.gov/pubmed/37226029 http://dx.doi.org/10.1007/s13311-023-01387-z |
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