Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice

Increased expression of the voltage-gated potassium channel Kv1.3 in activated microglia, and the subsequent release of pro-inflammatory mediators, are closely associated with the progression of Alzheimer’s disease (AD). Studies have shown that reducing neuroinflammation through the non-selective bl...

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Detalles Bibliográficos
Autores principales: Pan, Yijun, Kagawa, Yoshiteru, Sun, Jiaqi, Lucas, Deanna S. Deveson, Takechi, Ryusuke, Mamo, John C. L., Wai, Dorothy C. C., Norton, Raymond S., Jin, Liang, Nicolazzo, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457257/
https://www.ncbi.nlm.nih.gov/pubmed/37226029
http://dx.doi.org/10.1007/s13311-023-01387-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457257/
https://www.ncbi.nlm.nih.gov/pubmed/37226029
http://dx.doi.org/10.1007/s13311-023-01387-z

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