A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets

Identification of gene-by-environment interactions (GxE) is crucial to understand the interplay of environmental effects on complex traits. However, current methods evaluating GxE on biobank-scale datasets have limitations. We introduce MonsterLM, a multiple linear regression method that does not re...

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Detalles Bibliográficos
Autores principales: Di Scipio, Matteo, Khan, Mohammad, Mao, Shihong, Chong, Michael, Judge, Conor, Pathan, Nazia, Perrot, Nicolas, Nelson, Walter, Lali, Ricky, Di, Shuang, Morton, Robert, Petch, Jeremy, Paré, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457310/
https://www.ncbi.nlm.nih.gov/pubmed/37626057
http://dx.doi.org/10.1038/s41467-023-40913-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457310/
https://www.ncbi.nlm.nih.gov/pubmed/37626057
http://dx.doi.org/10.1038/s41467-023-40913-7

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