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N(6)-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming

Aerobic glycolysis has been considered as a hallmark of colorectal cancer (CRC). However, the potential functional regulators of glycolysis in CRC remains to be elucidated. In the current study, we found that Regenerating islet-derived protein 1-alpha (REG1α) was significantly increased in both CRC...

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Detalles Bibliográficos
Autores principales: Zhou, Mingxia, He, Jing, Li, Yingxia, Jiang, Libin, Ran, Jiaxuan, Wang, Chang, Ju, Chenxi, Du, Dan, Xu, Xinyu, Wang, Xuexin, Li, Hongle, He, Fucheng, Wen, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457312/
https://www.ncbi.nlm.nih.gov/pubmed/37626036
http://dx.doi.org/10.1038/s41419-023-06067-6