Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans

The sterol regulatory element binding proteins (SREBPs) are transcription factors that govern cholesterol and fatty acid metabolism. We recently identified SPRING as a post-transcriptional regulator of SREBP activation. Constitutive or inducible global ablation of Spring in mice is not tolerated, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Hendrix, Sebastian, Kingma, Jenina, Ottenhoff, Roelof, Valiloo, Masoud, Svecla, Monika, Zijlstra, Lobke F., Sachdev, Vinay, Kovac, Kristina, Levels, Johannes H. M., Jongejan, Aldo, de Boer, Jan F., Kuipers, Folkert, Rimbert, Antoine, Norata, Giuseppe D., Loregger, Anke, Zelcer, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457316/
https://www.ncbi.nlm.nih.gov/pubmed/37626055
http://dx.doi.org/10.1038/s41467-023-40943-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457316/
https://www.ncbi.nlm.nih.gov/pubmed/37626055
http://dx.doi.org/10.1038/s41467-023-40943-1

Ejemplares similares