Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice

Alzheimer’s disease, the most common age-related neurodegenerative disease, is characterized by tau aggregation and associated with disrupted circadian rhythms and dampened clock gene expression. REV-ERBα is a core circadian clock protein which also serves as a nuclear receptor and transcriptional r...

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Detalles Bibliográficos
Autores principales: Lee, Jiyeon, Dimitry, Julie M., Song, Jong Hee, Son, Minsoo, Sheehan, Patrick W., King, Melvin W., Travis Tabor, G., Goo, Young Ah, Lazar, Mitchell A., Petrucelli, Leonard, Musiek, Erik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457319/
https://www.ncbi.nlm.nih.gov/pubmed/37626048
http://dx.doi.org/10.1038/s41467-023-40927-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457319/
https://www.ncbi.nlm.nih.gov/pubmed/37626048
http://dx.doi.org/10.1038/s41467-023-40927-1

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