Single-cell lipidomics enabled by dual-polarity ionization and ion mobility-mass spectrometry imaging

Single-cell (SC) analysis provides unique insight into individual cell dynamics and cell-to-cell heterogeneity. Here, we utilize trapped ion mobility separation coupled with dual-polarity ionization mass spectrometry imaging (MSI) to enable high-throughput in situ profiling of the SC lipidome. Multi...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Liu, Yuan, Fields, Lauren, Shi, Xudong, Huang, Penghsuan, Lu, Haiyan, Schneider, Andrew J., Tang, Xindi, Puglielli, Luigi, Welham, Nathan V., Li, Lingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457347/
https://www.ncbi.nlm.nih.gov/pubmed/37626051
http://dx.doi.org/10.1038/s41467-023-40512-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457347/
https://www.ncbi.nlm.nih.gov/pubmed/37626051
http://dx.doi.org/10.1038/s41467-023-40512-6

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