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Immunogenicity of a Plasmodium vivax vaccine based on the duffy binding protein formulated using adjuvants compatible for use in humans

The invasion of reticulocytes by Plasmodium vivax merozoites is dependent on the interaction of the Plasmodium vivax Duffy Binding Protein (PvDBP) with the Duffy antigen receptor for chemokines (DARC). The N-terminal cysteine-rich region II of PvDBP (PvDBPII), which binds DARC, is a leading P. vivax...

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Detalles Bibliográficos
Autores principales: Martinez, Francisco J., Guillotte-Blisnick, Micheline, Huon, Christèle, England, Patrick, Popovici, Jean, Laude, Hélène, Arowas, Laurence, Ungeheuer, Marie-Noëlle, Reimer, Jenny M., Carter, Darrick, Reed, Steve, Mukherjee, Paushali, Chauhan, Virander S., Chitnis, Chetan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457348/
https://www.ncbi.nlm.nih.gov/pubmed/37626150
http://dx.doi.org/10.1038/s41598-023-40043-6