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Immunogenicity of a Plasmodium vivax vaccine based on the duffy binding protein formulated using adjuvants compatible for use in humans
The invasion of reticulocytes by Plasmodium vivax merozoites is dependent on the interaction of the Plasmodium vivax Duffy Binding Protein (PvDBP) with the Duffy antigen receptor for chemokines (DARC). The N-terminal cysteine-rich region II of PvDBP (PvDBPII), which binds DARC, is a leading P. vivax...
Autores principales: | Martinez, Francisco J., Guillotte-Blisnick, Micheline, Huon, Christèle, England, Patrick, Popovici, Jean, Laude, Hélène, Arowas, Laurence, Ungeheuer, Marie-Noëlle, Reimer, Jenny M., Carter, Darrick, Reed, Steve, Mukherjee, Paushali, Chauhan, Virander S., Chitnis, Chetan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457348/ https://www.ncbi.nlm.nih.gov/pubmed/37626150 http://dx.doi.org/10.1038/s41598-023-40043-6 |
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