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Ferroptosis contributes to ethanol-induced hepatic cell death via labile iron accumulation and GPx4 inactivation
Alcohol abuse is a significant cause of global morbidity and mortality, with alcoholic liver disease (ALD) being a common consequence. The pathogenesis of ALD involves various cellular processes, including oxidative stress, inflammation, and hepatic cell death. Recently, ferroptosis, an iron-depende...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457354/ https://www.ncbi.nlm.nih.gov/pubmed/37626043 http://dx.doi.org/10.1038/s41420-023-01608-6 |