Ferroptosis contributes to ethanol-induced hepatic cell death via labile iron accumulation and GPx4 inactivation

Alcohol abuse is a significant cause of global morbidity and mortality, with alcoholic liver disease (ALD) being a common consequence. The pathogenesis of ALD involves various cellular processes, including oxidative stress, inflammation, and hepatic cell death. Recently, ferroptosis, an iron-depende...

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Detalles Bibliográficos
Autores principales: Luo, Jiao, Song, Ge, Chen, Ningning, Xie, Mengyue, Niu, Xuan, Zhou, Shuyue, Ji, Yanan, Zhu, Xiaoxiao, Ma, Wanli, Zhang, Qianqian, Yu, Dianke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457354/
https://www.ncbi.nlm.nih.gov/pubmed/37626043
http://dx.doi.org/10.1038/s41420-023-01608-6

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