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Suppressed Akt/GSK-3β/β-catenin signaling contributes to excessive adipogenesis of fibro-adipogenic progenitors after rotator cuff tears

Muscular fatty infiltration is a common and troublesome pathology after rotator cuff tears (RCT), which mainly derives from fibro-adipogenic progenitors (FAPs). Compared to the RCT, fatty infiltration is not so severe in Achilles tendon tears (ATT). The knowledge of why fatty infiltration is more li...

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Detalles Bibliográficos
Autores principales: Lin, Xingzuan, Wang, Peng, Wang, Wei, Zhou, Hao, Zhu, Siyuan, Feng, Shujing, Chen, Yuzhou, Zhou, Han, Wang, Qichao, Xin, Hanlong, Shao, Xiexiang, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457376/
https://www.ncbi.nlm.nih.gov/pubmed/37626040
http://dx.doi.org/10.1038/s41420-023-01618-4