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The m6A modification-mediated OGDHL exerts a tumor suppressor role in ccRCC by downregulating FASN to inhibit lipid synthesis and ERK signaling

Metabolic reprogramming is a hallmark of cancer, and the impact of lipid metabolism as a crucial aspect of metabolic reprogramming on clear cell renal cell carcinoma (ccRCC) progression has been established. However, the regulatory mechanisms underlying the relationship between metabolic abnormaliti...

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Detalles Bibliográficos
Autores principales: Shi, Jian, Miao, Daojia, Lv, Qingyang, Wang, Keshan, Wang, Qi, Liang, Huageng, Yang, Hongmei, Xiong, Zhiyong, Zhang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457380/
https://www.ncbi.nlm.nih.gov/pubmed/37626050
http://dx.doi.org/10.1038/s41419-023-06090-7