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Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium

Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies. Ex vivo erythropoiesis from PSCs is currently limited by the low efficiency of functional RBCs with β-globin expression in...

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Detalles Bibliográficos
Autores principales: Jeon, Soo-Been, Koh, Hyebin, Han, A-Reum, Kim, Jieun, Lee, Sunghun, Lee, Jae-Ho, Im, Seung-Soon, Yoon, Young-sup, Lee, Jong-Hee, Lee, Ji Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457393/
https://www.ncbi.nlm.nih.gov/pubmed/37626061
http://dx.doi.org/10.1038/s41536-023-00320-4