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Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium
Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies. Ex vivo erythropoiesis from PSCs is currently limited by the low efficiency of functional RBCs with β-globin expression in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457393/ https://www.ncbi.nlm.nih.gov/pubmed/37626061 http://dx.doi.org/10.1038/s41536-023-00320-4 |