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Metformin as a promising target for DPP4 expression: computational modeling and experimental validation

Metformin is a regularly prescribed and low-cost generic medication. Metformin has been proposed as a target for Dipeptidyl-peptidase 4 (DPP4) expression in various clinical disorders. We provide insilco investigations on molecular docking and dynamic modeling of metformin and DPP4 potential interac...

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Detalles Bibliográficos
Autores principales: El-Arabey, Amr Ahmed, Zhang, Haiyan, Abdalla, Mohnad, Al-Shouli, Samia T., Alkhalil, Samia S., Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457412/
https://www.ncbi.nlm.nih.gov/pubmed/37624423
http://dx.doi.org/10.1007/s12032-023-02140-4