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Anticonvulsant effects of cenobamate in chemically and electrically induced seizure models in rodents

BACKGROUND: Cenobamate is an antiseizure medication used to treat partial-onset (focal) seizures. It is a molecule with one chiral center and a unique dual mechanism of action: enhancement of fast and slow inactivation of sodium channels with preferential inhibition of the persistent current and pos...

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Detalles Bibliográficos
Autores principales: Melnick, Susan M., Shin, Yujin, Glenn, Kelli J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457417/
https://www.ncbi.nlm.nih.gov/pubmed/37636350
http://dx.doi.org/10.1016/j.heliyon.2023.e18920