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YTHDC2 inhibits rat bone mesenchymal stem cells osteogenic differentiation by accelerating RUNX2 mRNA degradation via m6A methylation

As the most abundant internal mRNA modification, N6-methyladenosine (m6A) RNA methylation has been found to influence many biological events including bone mesenchymal stem cells (BMSCs) osteogenic differentiation. YTH N6-methyladenosine RNA binding protein C2 (YTHDC2) is an m6A reading protein with...

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Detalles Bibliográficos
Autores principales: Ma, Bo, Cao, Pei, Zhang, Lichen, Zhu, Hongyi, Ye, Xuwen, Wang, Lingjun, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457424/
https://www.ncbi.nlm.nih.gov/pubmed/37636387
http://dx.doi.org/10.1016/j.heliyon.2023.e18876