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Metabolic reprogramming in inflammatory microglia indicates a potential way of targeting inflammation in Alzheimer's disease

Microglia activation drives the pro-inflammatory activity in the early stages of Alzheimer's disease (AD). However, the mechanistic basis is elusive, and the hypothesis of targeting microglia to prevent AD onset is little explored. Here, we demonstrated that upon LPS exposure, microglia shift t...

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Detalles Bibliográficos
Autores principales: Sangineto, Moris, Ciarnelli, Martina, Cassano, Tommaso, Radesco, Antonio, Moola, Archana, Bukke, Vidyasagar Naik, Romano, Antonino, Villani, Rosanna, Kanwal, Hina, Capitanio, Nazzareno, Duda, Loren, Avolio, Carlo, Serviddio, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457454/
https://www.ncbi.nlm.nih.gov/pubmed/37586250
http://dx.doi.org/10.1016/j.redox.2023.102846