Concurrent predictors of an immune responsive tumor microenvironment within tumor mutational burden-high breast cancer

BACKGROUND: Data supporting high tumor mutational burden (TMB-H) as a lone biomarker for an immune-responsive tumor microenvironment (TME) in metastatic breast cancer (MBC) are weak, yet tumor agnostic approval in TMB-H advanced tumors provides immune checkpoint inhibition (ICI) as a clinical option...

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Detalles Bibliográficos
Autores principales: Sammons, Sarah, Elliott, Andrew, Barroso-Sousa, Romualdo, Chumsri, Saranya, Tan, Antoinette R., Sledge, George W., Tolaney, Sara M., Torres, Evanthia T. Roussos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457522/
https://www.ncbi.nlm.nih.gov/pubmed/37637072
http://dx.doi.org/10.3389/fonc.2023.1235902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457522/
https://www.ncbi.nlm.nih.gov/pubmed/37637072
http://dx.doi.org/10.3389/fonc.2023.1235902

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