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Improvement of Precision in Recombinant Adeno-Associated Virus Infectious Titer Assay with Droplet Digital PCR as an Endpoint Measurement

Recombinant adeno-associated virus (rAAV) has been utilized successfully for in vivo gene delivery for treatment of a variety of human diseases. To sustain the growth of recombinant AAV gene therapy products, there is a critical need for the development of accurate and robust analytical methods. Fif...

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Detalles Bibliográficos
Autores principales: Duong, Tam, McAllister, James, Eldahan, Khalid, Wang, Jennifer, Onishi, Eric, Shen, Kate, Schrock, Robert, Gu, Bingnan, Wang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457655/
https://www.ncbi.nlm.nih.gov/pubmed/37276150
http://dx.doi.org/10.1089/hum.2023.014