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scNCL: transferring labels from scRNA-seq to scATAC-seq data with neighborhood contrastive regularization

MOTIVATION: scATAC-seq has enabled chromatin accessibility landscape profiling at the single-cell level, providing opportunities for determining cell-type-specific regulation codes. However, high dimension, extreme sparsity, and large scale of scATAC-seq data have posed great challenges to cell-type...

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Detalles Bibliográficos
Autores principales: Yan, Xuhua, Zheng, Ruiqing, Chen, Jinmiao, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457667/
https://www.ncbi.nlm.nih.gov/pubmed/37584660
http://dx.doi.org/10.1093/bioinformatics/btad505