Long-term muscle-specific overexpression of DOK7 in mice using AAV9-tMCK-DOK7

Neuromuscular junction (NMJ) dysfunction underlies several diseases, including congenital myasthenic syndromes (CMSs) and motor neuron disease (MND). Molecular pathways governing NMJ stability are therefore of interest from both biological and therapeutic perspectives. Muscle-specific kinase (MuSK)...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Ting, Crick, Hannah R., Chaytow, Helena, van der Hoorn, Dinja, Alhindi, Abrar, Jones, Ross A., Hector, Ralph D., Cobb, Stuart R., Gillingwater, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457688/
https://www.ncbi.nlm.nih.gov/pubmed/37637210
http://dx.doi.org/10.1016/j.omtn.2023.07.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457688/
https://www.ncbi.nlm.nih.gov/pubmed/37637210
http://dx.doi.org/10.1016/j.omtn.2023.07.036

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