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Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: II. Antidepressant Effect in an Experimental Animal Model

Depression is a serious mental disorder and the most prevalent cause of disability and suicide worldwide. Quercetin (QER) demonstrated antidepressant effects in rats exhibiting anxiety and depressive-like behaviors. In an attempt to improve QER’s antidepressant activity, a QER-loaded transferosome (...

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Detalles Bibliográficos
Autores principales: Elkomy, Mohammed H., Abo El-Ela, Fatma I., Zaki, Randa Mohammed, Alsaidan, Omar A., Elmowafy, Mohammed, Zafar, Ameeduzzafar, Shalaby, Khaled, Abdelgawad, Mohamed A., Omar, Hany A., Salama, Rania, Eid, Hussein M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457845/
https://www.ncbi.nlm.nih.gov/pubmed/37631309
http://dx.doi.org/10.3390/pharmaceutics15082095