HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France)

In this work we investigated, for the first time, the effect of Plagius flosculosus (L.) Alavi & Heywood, a Sardinian–Corsican endemic plant, on HIV-1 integrase (IN) activity. The phytochemical analysis of the leaves chloroform extract led us to isolate and characterize three compounds (SPK1, SP...

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Detalles Bibliográficos
Autores principales: Sanna, Cinzia, D’Abrosca, Brigida, Fiorentino, Antonio, Giammarino, Federica, Vicenti, Ilaria, Corona, Angela, Caredda, Alessia, Tramontano, Enzo, Esposito, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457970/
https://www.ncbi.nlm.nih.gov/pubmed/37631033
http://dx.doi.org/10.3390/ph16081118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457970/
https://www.ncbi.nlm.nih.gov/pubmed/37631033
http://dx.doi.org/10.3390/ph16081118

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